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    Spectator
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    in reply to: Phages #1697

    Although promising, phage therapy still retains certain constraints, as strain-specificity and considerable antigenicity. What are the recent advances on the field? Do they allow its general clinical use?

    Avatarrdacosta
    Spectator
    Post count: 5
    in reply to: Immunomodulators #1696

    Can we better exploit immune-based Tools to figh off bacterial disease?

    Avatarrdacosta
    Spectator
    Post count: 5
    in reply to: Peptides #1695

    The review from Otvos, Laszlo. 2017. “Racing on the Wrong Track.” Frontiers in Chemistry 5(June): 1–4 suggests a strong effect of antimicrobial peptides on host functions rather than bacterial survival. In this scenario, they could be used in combination with existing antibiotics. Are there any data in this field?

    Avatarrdacosta
    Spectator
    Post count: 5
    in reply to: In vitro models #1694

    The 3D cell culture models seem to be more predictive of in vivo tissue responses than the 2D cell monolayer culture. Are there high-throughput screening platforms based on this approach?

    Avatarrdacosta
    Spectator
    Post count: 5

    What existing drugs can be repurposed for the WHO’s list of priority pathogens?

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