Although promising, phage therapy still retains certain constraints, as strain-specificity and considerable antigenicity. What are the recent advances on the field? Do they allow its general clinical use?
The review from Otvos, Laszlo. 2017. “Racing on the Wrong Track.” Frontiers in Chemistry 5(June): 1–4 suggests a strong effect of antimicrobial peptides on host functions rather than bacterial survival. In this scenario, they could be used in combination with existing antibiotics. Are there any data in this field?
What existing drugs can be repurposed for the WHO’s list of priority pathogens?
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