Professor Patrice Courvalin is an internationally recognized expert in the genetics and biochemistry of antibiotic resistance, and in the transfer and heterologous expression of genetic information. He first described and then elucidated, vancomycin resistance in Enterococcus.
Patrice’s research has led to a revision of the dogma describing natural dissemination of antibiotic-resistance genes. He and his colleagues demonstrated that a wide variety of pathogenic bacteria can promiscuously exchange genetic material, and proved that conjugation could account for dissemination of genes between phylogenetically remote bacterial genera.
The group has also elucidated the transposition mechanism of conjugative transposons from Gram-positive cocci, and more recently, obtained direct gene and protein transfer from bacteria to mammalian cells.
Patrice is currently Emeritus Professor in the Department of Microbiology and Head of the Antibacterial Agents Unit at the Institut Pasteur in France. He is also the Director of the International Course on Antibiotics and Resistance (ICARe).
Since 1970, Patrice has held many positions at the Institut Pasteur, including Chairman of the Department of Fundamental and Medical Microbiology. He was a Research Associate at the University of Wisconsin–Madison, and was Visiting Scholar in the Department of Biology, University of California-San Diego.
Patrice was awarded 15 scientific prizes and is a fellow of the American Academy of Microbiology; the Royal Academy of Medicine, Sarragossa; the Royal College of Physicians, London, and is an honorary member of the Australian Society for Antimicrobials.
He serves on the editorial board of several international journals in microbiology and infectious diseases; has published 342 papers, nine books and is inventor on two patents.
Patrice received his master’s degrees in sciences and in human biology from the University of Sciences in Paris, his Doctorate in Medical Sciences cum laude from the Medical School in Paris and was a medical resident at the Hôpital de l’Institut Pasteur.