AntibioticDB is an open-access database that catalogues and describes known antibacterial agents, consolidating data from diverse sources that include the primary research literature, patents and conference abstracts.
Initial development and curation of AntibioticDB was supported by the British Society for Antimicrobial Chemotherapy (March 2017 to June 2019) and curation led by Laura Piddock. Since 2022, further evolution of the AntibioticDB database and website has been led by GARDP, with curation overseen by Professor Alex O’Neill (University of Leeds, UK).
The information provided in AntibioticDB intends to serve both as a reference and a source of starting points for future research and (re-)development of antibacterial therapeutics. Within its 3000+ entries, AntibioticDB not only captures compounds that have reached preclinical/clinical development or are licensed for clinical use, but also includes experimental antibacterial agents. Whilst many entries in AntibioticDB are classical ‘antibiotics’ (small molecules that directly inhibit or kill bacteria), the database also includes a diverse range of non-canonical antibacterial agents (e.g., anti-virulence compounds, antibodies, bacteriophages, host-directed agents).
