Definition:
Antimicrobial peptides (AMPs) are short (5-50 amino acids) and normally cationic and amphipathic (with some exceptions), naturally occurring proteins that play a crucial role in the innate immune system of most organisms by defending against a broad spectrum of pathogens, including bacteria, viruses, fungi, and parasites. They typically exhibit rapid action and can disrupt microbial membranes, inhibit cell wall synthesis, or interfere with intracellular processes. AMPs are found across a wide range of organisms and are considered potential candidates for developing new antimicrobial therapies, particularly in the face of increasing antibiotic resistance.