Definition:
Methods to assess a chemical compound’s effect on a human or animal cell to separate toxic from nontoxic materials, providing predictive evidence of compound safety.
A wide range of assays measuring different aspects of cell death is available in the market and described in the literature. Cellular toxicity can be detected by monitoring structural changes or measuring parameters associated with loss of cell membrane integrity as detected by measuring the movements of molecules into and out of the cell across a damaged cell membrane.
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