Gram-negative bacterium that causes gonorrhoea, an important and frequently multidrug-resistant sexually transmitted infection.

Neisseria gonorrhoeae has progressively developed resistance to many different antibiotics. Cephalosporins are the only class of drug retaining efficacy against most N. gonorrhoeae. However, decreasing sensitivity has been observed to ceftriaxone, leading to treatment failures, and raising the prospect of untreatable infections. N. gonorrhoeae is classified as “high priority” on the WHO’s priority pathogens list for R&D of new antibiotics.