Polarity

Molecular property used for the prediction of permeability.

Polarity is an important property for entering the Gram-negative bacterial cell as well as oral bioavailability.

Molecular descriptors for polarity (Future Medicinal Chemistry, 2016)

The relationship between target-class and the physicochemical properties of antibacterial drugs (Bioorganic & Medicinal Chemistry, 2015)

Physicochemical properties of antibacterial compounds: implications for drug discovery (Journal of Medical Chemistry, 2008)