Selective sweep

Evolutionary process in which a new adaptive mutation arises and spreads through a population, causing a corresponding reduction in genetic diversity around the adaptive site.

Different evolutionary models can predict genome-wide selective sweeps vs gene-specific sweeps which may apply to different populations coexisting in the same environment. Population genetics can be used to study the evolution of drug resistance.

Selective Sweeps (Genetics, 2019)

Gene-specific Selective Sweeps in Bacteria and Archaea Caused by Negative Frequency-Dependent Selection (BMC Biology, 2015)

Genome-wide Selective Sweeps and Gene-specific Sweeps in Natural Bacterial Populations (The ISME Journal, 2015)

The Population Genetics of Drug Resistance Evolution in Natural Populations (Molecular Ecology, 2016)