S. aureus is a common commensal bacterium. However, it can cause infections in the bloodstream, skin- and soft tissue, as well as other body sites. It is also an important cause of infections associated with implants and medical devices.
Methicillin-resistant S. aureus (MRSA) is an important cause of hospital-acquired infections (HAIs) and community-acquired MRSA infections have also been detected. Methicillin resistance is generally associated with the presence of the mecA gene, part of a mobile genetic element known as the staphylococcal cassette chromosome mec (SCCmec).