Population PK/PD modelling

Studying pharmacokinetics/pharmacodynamics (PK/PD) correlations using mathematical models to describe PK data at the population level.

Population PK/PD modelling uses population pharmacokinetics in which data from all individuals in a population are evaluated simultaneously. In contrast to individual PK analysis, population PK modelling approaches rely on concentration-time data from multiple individuals and often utilize pooled data from more than one study. Using the information provided by the population PK model, appropriate dosages can be selected for a given population or subgroup.

Basic Concepts in Population Modeling, Simulation, and Model-Based Drug Development (CPT: Pharmacometrics & Systems Pharmacology, 2012)

Basic Concepts in Population Modeling, Simulation, and Model-Based Drug Development (2) (CPT: Pharmacomentrics and Systemy Pharmacology, 2013)

Guidance for Industry – Population Pharmacokinetics

Models for antimicrobial R&D: Computational modelling for population PK and PKPD (Revive webinar)