Speakers:

  • Dee Shortridge, Senior Director, JMI Laboratories (USA)
  • Rafael Cantón, Head of Clinical Microbiology Department, Hospital Universitario Ramón y Cajal; Associated Profesor, Complutense University Madrid (Spain)

Moderator:

  • Christian Giske, Professor/Chief consultant physician, Department of Laboratory Medicine, Karolinska Institutet (Sweden)

Presentation 1: Pre-clinical antimicrobial susceptibility testing: considerations and challenges (Dee Shortridge)

  • Steps for developing an in vitro susceptibility test for your lead compound
  • Studies needed to characterize your compound
  • Points to consider if your compound is not typical

Presentation 2: Pitfalls and opportunities of susceptibility testing in clinical trials of new antibiotics (Rafael Cantón)

  • The introduction of new antimicrobials needs antimicrobial susceptibility testing to define their profile and the alignment with regulators.
  • Susceptibility testing data are also used to define both clinical and PK/PD breakpoints.
  • Moreover, they can be used to recognize wild type populations and anticipate emergence or resistance.

This live webinar including an interactive Q&A session was broadcast on 2 March 2023.

If you have questions or comments, please let us know: revive@gardp.org.

Find the speakers’ slides here
Find the speakers’ responses to remaining audience questions here