- Sylvain Moineau, Professor and Canada Research Chair in Bacteriophages, Laval University (Canada)
- Ioanna Mela, Royal Society University Research Fellow and Assistant Professor, Department of Pharmacology University of Cambridge (United Kingdom)
- Claus-Michael Lehr, Professor of Pharmacy and Head of the Department Drug Delivery across Biological Barriers Helmholtz Institute for Pharmaceutical Research (Germany)
Moderator: Laura Piddock, Scientific Director, GARDP (Switzerland)
Presentation 1: Targeted approach: Phages as delivery system (Sylvain Moineau)
- Viruses are the most abundant and diverse biological entities on the planet. Phages can target and kill bacteria with greater specificity than antibiotics. Sylvain discussed phage-based options and recent biotechnology advancements in phage engineering that can be leveraged to deliver antibacterials, including CRISPR-Cas systems.
Presentation 2: DNA nanostructures for antimicrobial drug delivery (Ioanna Mela)
- DNA nanostructures can be easily made and functionalized with active molecules
- We have shown that aptamer-functionalized nanostructures can specifically target bacteria
- Targeted drug delivery can potentiate active molecules and give a new lease of life to existing antimicrobials
Presentation 3: Nanocarrriers and complex in-vitro models for drug delivery across biological barriers in infectious diseases (Claus-Michael Lehr)
- Predicting & optimizing intra-bacterial delivery of anti-infectives across the gram-negative bacterial cell envelope
- Targeted delivery of nanocarriers to skin hair follicles
- Combatting infectious diseases of the lung – growing bacterial biofilms on human lung epithelial cells and biofilm-pentrating nanocarriers
This live webinar including an interactive Q&A session was broadcast on 24 January 2023.
If you have questions or comments, please let us know: email@example.com.