Information:

The first free, open-access database of antibacterial compounds, including discontinued agents, drugs under pre-clinical development and those in clinical trials. This database includes over 1000 compounds which are in one of the following categories:

  • Currently in pre-clinical development
  • In phases 1-3 of clinical trials
  • In phase 4 of clinical development either awaiting approval, or recently approved.
  • The compound has been discontinued

This intends to serve as reference or as starting points for future research and re-development.

Access this database here: https://www.antibioticdb.com/

More information:

Revitalizing the drug pipeline: AntibioticDB, an open access database to aid antibacterial research and development (Journal of Antimicrobial Chemotherapy, 2018)

AntibioticDB Demonstration with Laura Piddock (BSAC, 2017)

Tags:
External resource, Database, Publication, Discovery, Hit-to-lead, Lead-to-candidate, Preclinical development, Screening, Acinetobacter baumannii, Enterobacteriaceae, Enterococcus faecium, Escherichia coli, ESKAPE, Gram negative, Gram positive, Klebsiella pneumoniae, MDR, Pseudomonas aeruginosa, Staphylococcus aureus, WHO priority pathogens, Aminoglycosides, Carbapenems, Cephalosporins, Diarylquinolines, Glycopeptides, Lincomycins, Macrolides, Penicillins, Quinolones, Sulfonamides, Tetracyclines