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Converting Gram-positive-only compounds into broad-spectrum antibiotics


Speaker: Paul Hergenrother, Kenneth L. Rinehart Endowed Chair in Natural Products Chemistry, Department of Chemistry and the Institute for Genomic Biology, University of Illinois, US

Moderator: Laura Piddock, Director of Scientific Affairs, GARDP

In this webinar, Paul detailed his research group’s efforts to understand compound accumulation in the Gram-negative ESKAPE pathogens. Emphasis was placed on the practicality, actionability, and translatability of this information, specifically, the use of accumulation rules to convert high-value Gram-positive-only compounds into antibiotics with activity against key Gram-negative pathogens.

The presentation was followed by a Q&A session.


This live webinar including interactive Q&A session was broadcast on 7 November 2019.

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2019-11-08T15:36:09+00:00