Speakers:

  • Kenneth (Ken) Bradley, Global Head, Infectious Disease Discovery, Roche (Switzerland)
  • Diarmaid Hughes, Professor of Medical Molecular Bacteriology, Uppsala University (Sweden)

Moderator:

  • Karen Bush, Professor of Practice in Biotechnology, Emerita, Indiana University (USA)

Presentation 1: Progression criteria and Go/NoGo decisions in antibacterial drug discovery – an industry view (Ken Bradley)

  • Drug discovery starts and ends with the patient.
  • Target product profiles (TPPs) guide R&D.
  • Target candidate profiles (TCPs) provide guidance and enable Go/NoGo decision making for preclinical programs.
  • Examples will be provided to showcase decision making in preclinical research.

Presentation 2: Progression criteria and Go/NoGo decisions in antibacterial drug discovery – an academic view (Diarmaid Hughes)

  • The academic research environment as it relates to antibiotic discovery.
  • Serendipity versus planning in academic antibiotic discovery.
  • The importance of projects like ENABLE in guiding academic researchers along the path to a useful drug.

This live webinar including an interactive Q&A session was broadcast on 9 April 2024.

If you have questions or comments, please let us know: revive@gardp.org.