A genus of non-motile, aerobic and facultatively anaerobic Gram-negative rod-shaped bacteria.
Klebsiella belongs to the Enterobacterales Enterobacteriaceae family. It is a common cause of both community-acquired and hospital-acquired infections, including pneumonia and respiratory tract infections.
Klebsiella is one of the ‘ESKAPE’ pathogens that make up the most common antibiotic-resistant infections. Multidrug-resistant and extensively drug-resistant Klebsiella are among the most challenging infections to treat. Carbapenem-resistant Enterobacteriaceae such as Klebsiella are categorized by WHO as a ‘priority 1 (critical)’ pathogen for R&D of new antibiotics.
Klebsiella species (K. pneumoniae, K. oxytoca, K. ozaenae and K. rhinoscleromatis) (Antimicrobe, 2017)
Surveillance of antimicrobial resistance in Europe (European CDC, 2018)
Klebsiella pneumoniae: a major worldwide source and shuttle for antibiotic resistance (FEMS Microbiology Reviews, 2017)
Klebsiella pneumoniae: Going on the Offense with a Strong Defense (Microbiology and Molecular Biology Reviews, 2016)