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Infection models for antimicrobial R&D: Intracellular models


Speaker: Françoise van Bambeke, Research Director Cellular and Molecular Pharmacology, Louvain Drug Research Institute, Université catholique de Louvain (Belgium)

Moderator: Laura Piddock, Director of Scientific Affairs, GARDP


In this webinar, Françoise van Bambeke talked about intracellular activity of antibiotics. Topics discussed included:

  1. The role of intracellular survival in chronic infections and its contribution to poor response to antibiotics
  2. In vitro models to study intracellular activity of antibiotics
  3. Cellular pharmacokinetic (PK) parameters predictive of intracellular potency for antibiotics
  4. Cellular pharmacodynamics (PD) parameters predictive of intracellular efficacy for antibiotics

This live webinar including interactive Q&A session was broadcast on 9 July 2019.

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2019-07-11T07:45:52+00:00